Standardization

Pharmacological activity

BOSWELLIA (Boswellia Serrata)

• Anti-inflammatory and analgesic properties;
• Treat articular and respiratory tracts inflammation;
• Antispasmodic.

YUZU (Citrus Junos) Origin: Japan

• Muscular relaxant;
• Helps memory and concentration.

MALIC ACID

• Has diuretic properties;
• Provides cellular energy and allows the glucose production.

KUDZU (Pueraria Lobata)

• Regularizes nervous transmissions;
• Allows the excretion of toxins and lactic acid.

HOP (Humulus Lupulus)

• Has relaxant, sedative and hypnotic properties;
• Supports digestion.

OFFICINAL PEONY (Paeonia Offi cinalis)

• Antispasmodic and sedative;
• Supports Acetylcholine production related to muscular contraction.

MAGNESIUM (chelated with amino acids)

• Contributes to nervous transmission;
• Contributes to muscular contractility;
• Contributes to the pH balance and is an enzyme cofactor;
• Is necessary for the calcium and vitamin C metabolisms.

COLEUS (Coleus Forskohlii)

• Helps calm muscular cramps;
• Supports muscular relief;
• Regularizes intracellular metabolism.

• Prolonged use (regular training, following muscular treatment, etc.): Take 1½ teaspoon (7,5 ml) daily.
• Unbearable pain use: Take 1½ teaspoon (7,5 ml) and keep under the tongue for a minimum of 30 seconds then swallow, 3 to 4 times daily, as needed. Switch to prolonged use.

• Must receive treatments from a specialist: physiotherapist, chiropractor, massotherapist, etc. in order to optimize their manipulations;
• Practice intense sports and suffer from stress cramps;
• Suffer from pain associated with post-traumatic lesion or injury;
• Suffer from impatient legs and/or night cramps.

CONTRAINDICATIONS

• Consult a health practitioner in case of serious pathologies or before combining with any other product or medicine
• Avoid giving to children under 18 years of age and to pregnant or breastfeeding women without the advice of your health practitioner;
• Cease the use and consult a health practitioner if the symptoms persist or if undesirable effects should occur.

DRUG INTERACTIONS

• Beta blockers, clonidine or hydralazine;
• Anticoagulants such as Coumadin and Warfarin (Clopidogrel), ticline (Ticlopidine) or trental (Pentoxifylline);
• Avoid using coleus forskohlii without the opinion of your health practitioner;
• In the event of serious disease or consumption with other medications, do not take this product without the consent of an expert healthcare professional.

SIDE EFFECTS

• Mild gastro-intestinal discomforts and skin allergies.

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• Schulz V, Hänsel R, Tyler VE. Rational Phytotherapy - A Physicians' Guide to Herbal Medicine, fourth edition, Springer, Germany, 2001.
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• Tanaka T., Maeda M., Kohno H., Murakami M., Kagami S., Miyake M., Wada K. Inhibition of azoxymethane-induced colon carcinogenesis in male F344 rats by the citrus limonoids obacunone and limonin. Carcinogenesis., 22, 193-198, (2000)
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• Jiang RW, Lau KM, Lam HM, Yam WS, Leung LK, Choi KL, Waye MM, Mak TC, Woo KS, Fung KP. Related Articles,
• A comparative study on aqueous root extracts of Pueraria thomsonii and Pueraria lobata by antioxidant assay and HPLC fingerprint analysis. J Ethnopharmacol. 2005 Jan 4;96(1-2):133-8.
• Lukas SE, Penetar D, Berko J, Vicens L, Palmer C, Mallya G, Macklin EA, Lee DY. Related Articles, Links An extract of the Chinese herbal root kudzu reduces alcohol drinking by heavy drinkers in a naturalistic setting.
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• DerMarderosian A et al. Indian Frankincense Tree, The Review of Natural Products - Facts and Comparisons,United States, 1998.
• Roberts AJ (Dir). Nutraceuticals - The complete encyclopedia of Supplements, Herbs, Vitamins and Healing Foods, Perigee Books, United States, 2001, p. 389.
• Schulz V, Hänsel R, Tyler VE. Rational Phytotherapy - A Physicians' Guide to Herbal Medicine, fourth edition, Springer, Germany, 2001.
• Alternative Medicine Review, Monograph Boswellia serrata. vol.3, Number 4, 1998. www.thorne.com
• The Natural Pharmacist (Ed). Natural Products Encyclopedia, Herbs & Supplements - Boswellia, ConsumerLab.com. www.consumerlab.com
• Therapeutic Research Faculty (Ed). Boswellia, Natural Medicines Comprehensive Database. www.naturaldatabase.com
• Yano M. Prevention by citrus. Nippon Shokuhin Kagaku Kogaku Kaishi, 49, 139-144 (2002)
• Hashinaga F., Herman Z, Hasegawa S. Limonoids in seeds of Yuzu, Nippon, Shokushin, Kogyo Gakkaishi, 37, 380-382 (1990)
• Hasegawa S, Ifuku Y. Biochemistery of citrus limonoids, Nippon Shokushin, Kogyo Gakkaishi, 41, 372-380 (1994) Tanaka T., Maeda M., Kohno
• H., Murakami M., Kagami S., Miyake M., Wada K. Inhibition of azoxymethane-induced colon carcinogenesis in male F344 rats by the citrus limonoids obacunone and limonin. Carcinogenesis., 22, 193-198, (2000)
• Baynes J, Dominiczak M. Medical Biochemistry. New York: Mosby; 1999:182-183.
• Fiume Z. Final report on the safety assessment of Malic Acid and Sodium Malate. Int J Toxicol. 2001;20 (Suppl 1):47-55.
• Russell IJ, Michalek JE, Flechas JD, Abraham GE. Treatment of fibromyalgia syndrome with Super Malic: a randomized, double-blind, placebocontrolled pilot study. J Rheumatol. 1995; 22:953-958.
• Young Z, Floyd DL, Loeber G, Tong L. Structure of a closed form of human malic enzyme and implications for catalytic mechanism. Nature Struct Biol. 2000; 7:251-257.-
• Young Z, Floyd DL, Loeber G, Tong L. Structure of a closed form of human malic enzyme and implications for catalytic mechanism. Nature Struct Biol. 2000; 7:251-257.
• Paddle BM, Haugaard N. Role of magnesium in effects of epinephrine on heart contraction and metabolism. Am J Physiol. 1971
• Oct;221(4):1178-84.
• Savabi F, Gura V, Bessman S, Brautbar N. Effects of magnesium depletion on myocardial high-energy phosphates and contractility. Biochem Med Metab Biol. 1988 Apr;39(2):131-9.

• Inflammation and pain: Inflamgo will help in the regeneration of joint cartilages and will contribute to slow down the inflammation cycle: pain = inflammation = + pain and + inflammation;

• Sprain, twist, elongation, cramps, etc, due to sporting practice. In combination with Inflamgo, Allevia will act as an analgesic, will bring fast and effective relief and will help reduce these symptoms in a drastic way;

• Sporting practices sometimes bring disadvantages such as cramps, articulary irritations, etc: Minero-Balance is a quality supplement  rich in minerals which will provide the necessary elements the body needs at times of demanding physical activity;

• Regular of specific sporting activity: Blitz is ideal to reconstitute and increase energy to its maximum level;

• Spasmophilia: Combine Muscle-Relax with Relaximum in order to reduce the symptoms related to stress and to reduce the frequency and intensity of crises;

• Raynaud’s disease: Combine Muscle-Relax with B-Balance.