Standardization

Plant / Ingrédient	Standardization	Qty of dried plant per 7,5 ml
Rice germ	GABA 40 %	1000 mg (germs)
Griffonia	5 HTP 5 %	475 mg (fruits)
Schisandra	Lignan 0,5 %	300 mg (fruits)
Maca	Glucosinolates 0,2 %	200 mg (roots)
Green tea	Polyphenols 5 %	100 mg (leaves)
Inositol hexaphosphate	N/A	100 mg
L-Glutamine	Aminoacid	100 mg

Pharmacological activity

The natural products and plants in this formulation are traditionally used for the following effects:

Rice Germ (Oryza Sativa)

Origin : Asia

• Provide GABA to the body, thus allowing to reduce anxiety;
• Inhibiting role in the mechanism of stress manifestation;
• Provide mental as well as physically peacefulness;
• Improve the quality of sleep.

GRIFFONIA (Griffonia Simplicifolia)

Origin: Africa

• Stimulate the production of serotonin, the hormone of pleasure;
• Help fight anxiety;
• Help fight depression;
• Support the proper functioning of the nervous system.

SCHIZANDRA (Schisandra Chinensis)

Origin: China

• Antistress properties;
• Antioxidant properties;
• Increase the vitality;
• Improve the temper.

MACA (Lepidium Meyenii)

Origin: Peru

• Stimulate the immune system and tone up the whole system;
• Increase the energy level;
• Stimulate and improve cognitive and memory functions.

GREEN TEA (Camellia Sinensis)

Origin: Asia

• Antioxidant and cellular protector;
• Sustain the dopamine production thus contributing to improve concentration;
• Metabolism accelerator of carbohydrates

INOSITOL HEXAPHOSPHATE

• Anxiolytic;
• Lipotropic factor;
• Antidepressant;
• Muscular relaxation agent

L-GLUTAMINE

• Provide energy to the brain.

Neurotonik may be used in several ways and in different occasions:

• Daily prolonged use: Prevention of depressive conditions or related to seasonal mood disorders, associated with a lack of sunshine: Take 1½ teaspoon (7,5 ml) daily.
• Panic or distress crisis use: For panic and anxiety, take immediately 1½ teaspoon (7,5 ml) and keep under the tongue for 30 to 60 seconds, then swallow, 2 to 4 times daily if needed, until the end of the crisis.
• Acute crisis use: Take 1½ teaspoon (7,5 ml), 3 times a day, at least 20 minutes before or 1 hour after a meal during 1 week. Then switch to prolonged use (above), during at least 1 month. Thereafter, progressively reduce dosage to reach the daily prolonged use posology.

How: Shake the bottle well, and content must be mixed with juice or water.

*Refrigerate after opening

The effect of Neurotonik is noticeable within minutes after ingestion. The optimal effect will be observed after a few weeks of daily use.

CONTRAINDICATIONS

Avoid giving in case of :

• Pregnancy and breastfeeding without the advice of your health practitioner;
• Bipolar or trisomic disorders;
• Following an organ transplant;
• Renal or hepatic insufficiency;
• Gastric or duodenal ulcer.
• Only consume under the supervision of a health practitioner

PRECAUTIONS

• Consult a health practitioner in case of: psychiatric pathologies, organ transplantation, anemia, ulcer, renal or hepatic insufficiencies or before combining with another product or medication;
• Cease the use and consult a health practitioner if the symptoms persist or if undesirable effects should occur;
• Avoid giving to children under 12 years of age.

* If the psychological state does not improve after a few weeks of use, please consult a health practitioner.

MEDICINAL INTERACTIONS

Avoid using with the following medications:

• Selective Serotonin Reuptake Inhibitors (SSRI);
• MAOI antidepressants type (only);
• Carbidopa;
• Cyclosporine;
• Lithium;
• Lactulose;
• Oral contraceptives;
• Increases the effect of antianxiolytics;
• Betablockers;
• Antiepileptic.

In the event of serious disease or consumption with other medications, do not take this product without the consent of an expert healthcare professional.

Do not use with the following herbs:

• St. John’s Wort, Ginseng (Radix panacis ginseng (Ren Shen);
• Wei Ling Xian, Tu Fu Ling, Shi Jun Zi, Fu Ling.

SIDE EFFECTS

• Gastric disorders;
• Suppression of appetite;
• More frequent and more abundant urination.

SPEED OF THE EFFECTS

Neurotonik produces two types of effects:

• A fast and almost immediate effect. It occurs half and hour to one hour after the first, second or third dose of the product. This effect is light, but perceptible. It decreases the feeling of sadness or blues which decreases during a few hours.
• A long-term effect which passes through the rehabilitation of the brain. In a way, the brain relearns how to naturally produce the principal neurotransmitters implied in mood. Their production regulates to a normal level for the individual. Fatigue, insomnia, lack of concentration, loss of appetite, etc. are attenuated or disappear by this fact.

This product is intended for individuals suffering of light to moderate depression. Individuals suffering from severe depression or having suicidal tendencies must obviously initially be treated with medication.

Neurotonik is recommended to all those who:

• Suffer from depression, depressive mood and anxiety and who do not appreciate the happy moments in life;
• Must be weaned from a medication that alters neurotransmitters: medication, cigarette, alcohol, narcotics, sleeping pills, etc.
• Suffer from a serious pathology or are recovering from injuries following an accident;
• Have lost interest for any kind of activities, which they used to enjoy: leisure activities, sports, arts, etc.
• Become abnormally a stay-at-home person and feel like doing nothing;
• Live through very difficult and painful periods such as: death, job loss, divorce, serious illness, disabling accidents, etc.
• Feel disillusioned facing their performances at work or at school, and are drastically moving towards depression, because of a total lack of interest.

Neurotonik will be effective for men as well as for women. Elderly who are bored and lonesome and have lost the will to live (neurotransmitters production can be affected by aging), those who lose weight without valid reason. All these people will fully profit from it.

SYNERGISTIC ACTION

A unidimensional action targeting only one neurotransmitter is not as effective as a global action implying several chemical messengers of the brain. There is more than 120 neurotransmitters, responsible of awakening, appetite, libido, mood, emotions, decision-making, thought, memory, etc This product acts simultaneously on 6 of the main neurotransmitters: dopamine (motor function), serotonin (the great inhibitor), GABA (relaxing agent), adrenaline (stress hormone), acetylcholine (memory agent) and noradrenalin (the carrot and the stick) i.e. the vasoconstrictor administrated in shock states, which no other chemical antidepressant currently does.

Moreover, Neurotonik reduces the harmful symptoms of depression, of which the cortisol production. Thus, it acts on the source of the problem.

Being adaptogens, plants entering in the composition of our product have multiple impacts on the chemistry of the brain. The raw substances contained in the aforementioned plants, provide to the brain the regulating factors necessary for the neurotransmitters production:

• GABA (in the rice germ) and saponides (in the suma) limit the cortisol accumulation by inhibition (blockage) at several operation levels (see fig. 1)
• Certain neurotransmitters act as stimulants, i.e. they produce depolarization. Some are inhibiting, i.e. they produce hyperpolarization. Others are either stimulant or inhibitory, depending on the receiver they interact with; this is the case with gamma-aminobutyric acid (GABA), which is a very widespread inhibitor in the neurons of the cortex, it regulates anxiety.
• Rice germ and the griffonia fruits are suppliers of two essential intermediaries for all cerebral circuits (GABA and 5-HTP) implied in the regulation process due to stress. They act upon the serotonin production called pleasure hormone, and inhibit the harmful effects induced by cortisol superaccumulation.
• 5-HTP increases the serotonin activity, the hormone produced in the brain which intervenes with mood, sleep and appetite. When serotonin rate is low, this leads to depression, worries and sleeping disorders. By its 5-HTP molecule, griffonia regulates the serotonin production which is responsible for good mood.
• In addition, L-glutamic acid is the major excitant associated to learning and memory. It is a precursor of GABA.

Together, these elements regulate the release of neurotransmitters and their balance in the brain. The synergistic action allows to increase the quantity of neurotransmitters, which is too low in the brain, like serotonin and dopamine, and to decrease the amount of those in greater quantities (cortisol). Consequently, this formulation allows the brain to produce a homeostatic quantity of neurotransmitters in a good balance, and to regulate their natural and biological production without any long-term help.

Q. Which therapeutic effects will I feel with Neurotonik ?

Neurotonik acts directly at the source of the problem, that is to say the disorder in the neurotransmitters production. Indeed, as mentioned above, depression just like the majority of the so called “mental” illnesses, finds its origin in the imbalance of the neurotransmitters production. Indeed, they act like chemical messengers of the brain. They are responsible for pleasure and positive perceptions of various life events. A reduction or suspension of the neurotransmitters production induces the symptoms of a nervous breakdown:

• Rebalance of the serotonin production, by improving the positive feedback felt by the patient. Mood is thus improved;
• Rebalance of the dopamine and noradrenalin production, by improving the energy level and positive feelings;
• Stimulation of the 5-HT1A receptors. This stimulation has a beneficial effect. It attenuates depression, anxiety and obsessive thoughts;
• Reduction in the cortisol level, resulting in the reduction of the harmful consequences of stress.

Neurotonik is non-addictive, since its action is multiple. To some extent it rehabilitates the brain. Contrary to traditional antidepressants providing to the brain the molecules which it ceased producing, Neurotonik stimulates the natural production of endogens of the brain, which is thus rehabilitated. Therefore, it is not a temporary support to depend on, but a long-term solution allowing the individual to regain an adequate balance in his cerebral chemistry. After a few months, this balance having returned, the patient does not need the product anymore.